Pitt innovators were issued 11 U.S. patents in January 2025.
Featured patent: 12,186,371: Biomarkers and Treatment Methods for Traumatic Brain Injury-Associated Impairments
Pitt innovators exploring the role of inflammation and autoimmune responses in traumatic brain injury have discovered that there is potential for immunotherapy treatments that support immune responses and promote neural repair. Recombinant humanized IL-7 (rhIL-7) shows promise as a treatment to enhance lymphoproliferation and adaptive immunity, potentially improving recovery and reducing complications when combined with TNFR1 inhibitors.
For more information on this technology, including licensing, contact us at partner@pitt.edu.
Below is a listing of all patents issued to Pitt innovators in January 2025. You can also search all Pitt technologies available for licensing.
| Patent number | Title | Inventor(s) | Licensing manager | Status |
|---|---|---|---|---|
| 12,202,811 | Compounds for Treating Prostate Cancer | Peter Wipf; Erin Skoda; Zhou Wang | Andrew Remes | Available for licensing |
| 12,201,687 | Compositions for Modulating an XBP1 Pathway in a Keratinocyte and Methods of Use | Louis Falo; Zhaoyang You | Andrew Remes | Available for licensing |
| 12,201,745 | Vascular Extracellular Matrix Hydrogel | Stephen Badylak; George Fercana; Thomas Gleason; Julie Phillippi | Alex Ducruet | Available for licensing |
| 12,194,033 | Glycine Receptor Modulators and Methods of Use | Pei Tang; Marta Wells; Yan Xu | Maria Vanegas | Available for licensing |
| 12,186,371 | Biomarkers and Treatment Methods for Traumatic Brain Injury-Associated Impairments | Amy Wagner | Andrew Remes | Available for licensing |
| 12,188,019 | Silencing of HNF4A-P2 Isoforms with siRNA to Improve Hepatocyte Function in Liver Failure | Jose Ballbe; Ramon Bataller | Katherine Gadacz | Available for licensing |
| 12,188,099 | Integrated Proviral Sequencing Assay | Kevin Joseph; John Mellors | Andrew Remes | Available for licensing |
| 12,208,857 | Modular Hand-Bike Pedal | Rory Cooper; Benjamin Gebrosky | Connor Perryman | Available for licensing |
| 12,194,201 | Silica Nanoparticle Doped Conductive Polymer | Xinyan Cui; Kevin Woeppel | Janice Panza | Available for licensing |
| 12,202,839 | In-Flow Photooxygenation of Aminothienopyridinones Generates Novel PTP4A3 Phosphatase Inhibitors | John Lazo; Ettore Rastelli; Elizabeth Sharlow; Nikhil Tasker; Peter Wipf | Andrew Remes | Licensed |
| 12,203,830 | Sensors with Dehumidifiers | Hou-Yu Chen; Sung Kwon Cho; Sean Hwang; Alexander Star | Janice Panza | Available for licensing |