The University of Pittsburgh announced that Pitt innovators were issued 6 U.S. patents in September 2021.
Featured Patent: 11,129,846 “Method of Treating Severe Asthma”
Severe asthma accounts for 5-10 percent of asthma sufferers, but consumes up to 50 percent of asthma-related healthcare costs of $28 billion per year. Corticosteroids, a mainstay of asthma therapy, are ineffective at treating severe asthma, leading to more frequent emergency care and hospitalization. The innovators have shown that expression of IFN-y is significantly reduced in IRF5-deficient mice. An intervention to block IRF5 function in the lungs of severe asthmatics is therefore a promising new therapeutic modality by preventing airway hyperactivity.
For more information on this technology, contact Maria Vanegas at mvanegas@innovation.pitt.edu.
Below is a list of patents issued to Pitt innovators in Septembert 2021.
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11,111,253 |
6-ARYL-7 Substituted-3-(1H-PYRAZOL-5-YL)-7-H-[1,2,4] TRIAZOLO [3,4-B] [1,3,4] Thiadiazines as Inhibitors of the Stat3 Pathway with Anti-Proliferative Activity | Donna Huryn; Peter Wipf; Jennifer Grandis; Matthew LaPorte; Paul Johnston; Mark Schurdak; Raffaele Colombo |
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Maria Vanegas | Available for licensing | ||
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11,117,936 |
Affinity-Enhanced Monomeric Streptavidin Chimeric Antigen Receptor (CAR) | Jason Lohmueller |
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Andrew Remes | Available for licensing | ||
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11,123,454 |
Biodegradable, Thermally Responsive Injectable Hydrogel for Treatment of Ischemic Cardiomyopathy | Tomo Yoshizumi; William Wagner; Yang Zhu; Hongbin Jiang |
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Janice Panza | Available for licensing | ||
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11,129,711 |
Double Component Mandrel for Electrospun Stentless, Multi-Leaflet Valve Fabrication | Antonio D’Amore; William Wagner; Vinay Badhwar; Young Jae Chun |
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Janice Panza | Licensed | ||
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11,129,875 |
Osteoarthritis Treatment with Chemokine-Loaded Alginate Microparticles | Riccardo Gottardi; Steven Little; Daniel Desantis; Mintai Hwang |
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Janice Panza | Available for licensing | ||
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11,129,846 |
Method of Treating Severe Asthma | Anuradha Ray; Timothy Oriss; Prabir Ray; Sally Wenzel |
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Maria Vanegas | Available for licensing | ||
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