Pitt innovators were issued eight U.S. patents in September 2025.
Featured patent: 12,421,178: Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds
University of Pittsburgh researchers led by professor in the Department of Chemistry, Kazunori Koide, have developed a novel method for performing the Birch reduction, a powerful synthetic chemistry transformation, without the need for liquid ammonia or cryogenic temperatures. This novel approach simplifies the Birch reduction process, making it more accessible and environmentally friendly while maintaining its effectiveness in chemical synthesis. This innovation opens new doors for applications in both academic and industrial settings, where safer and greener chemical processes for pharmaceutical synthesis and materials science are increasingly prioritized.
For more information on this technology, including licensing details, contact us at partner@pitt.edu.
Below is a listing of all patents issued in September 2025.
| Patent Number |
Title | Inventor(s) | Licensing Manager | Status | |||
| 12,424,617 | Novel Electro-Spun Sulfur Wire for Fabricating Mattes of Lithium-Sulfur Batteries | Pavithra Shanthi, Bharat Gattu, Prashant Kumta; Prashanth Hanumantha | Janice Panza | Available for Licensing | |||
| 12,419,998 | Tuning Adhesion at Contacting Device Interfaces: Geometric Tools for Minimizing Surface Fouling | Luka Pocivavsek; Edith Tzeng; Sang Ho Ye; William Wagner; Sachin Velankar | Janice Panza | Available for Licensing | |||
| 12,420,073 | Biosensor Tattoos and Uses Therefor for Biomarker Monitoring | Jonathan Jarvick; O. Burak Ozdoganlar; Phil Campbell; Geza Erdos; Louis Falo; Marcel Brunchez | Andrew Remes | Available for Licensing | |||
| 12,428,460 | Engineered TGF-Beta Monomers and Their Use for Inhibiting TGF-Beta Signaling | Traian Sulea; Andrew Hinck; | Maria Vanegas | Licensed | |||
| 12,421,525 | Conjugates Comprising AAVS and CAS9 Polypeptides | Timothy Day; Bilge Ozturk; Leah Byrne | Maria Vanegas | Optioned | |||
| 12,414,973 | Antigenically Stealthed Oncolytic Viruses | Doina Atanasiu ; Tina Cairns ; Gary Cohen; Bonnie Hall; Ceren Tuzmen; Joseph Glorioso III; Justus Cohen | Maria Vanegas | Available for Licensing | |||
| 12,428,378 | Methods and Materials for Increasing Level of Phosphorylation AMPK Protein | Beibei Chen; Toren Finkel; Yuan Liu | Maria Vanegas | Available for Licensing | |||
| 12,421,178 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | James Burrows; Kazunori Koide | Connor Perryman | Available for Licensing |