University of Pittsburgh Announces 15 Patents Issued to Pitt Innovators in October 2023

Posted on by Mike Yeomans

Pitt innovators were issued 15 U.S. patents in October 2023.

Featured Patent: 11,773,075: “Modulators of P97 AAA Atpase Activity”

Although recent evidence shows that inhibiting the protein p97 kills cancer cells, there are currently no drugs on the market that target p97 directly. Pitt innovators have discovered potent and specific p97 inhibitors that may lead to new treatments for cancer, and possibly also neurodegeneration and genetic disorders involving p97 mutations. Inhibition of p97 ATPase activity triggers downstream cellular effects, including the suppression of cellular proliferation that makes cancer such a dangerous disease. And because these compounds specifically inhibit p97, they offer the possibility of treating a wide array of ailments with fewer side effects than drugs acting on broader pathways, such as neurodegenerative diseases

For more information on this technology, including licensing, contact us at partner@pitt.edu.

Below is a listing of all patents issued to Pitt innovators in September 2023. You can also search all available Pitt technologies.

 

Patent
Number		 Title   Inventor(s)   Licensing Manager        Status
 
11,773,010 High Transparency, High Haze Nanostructured Structures Sajad Haghanifar; Paul Leu; Tongchuan Gao; Bradley Pafchek George Coulston Available for Licensing
 
11,771,555 Retrievable Self-Expanding Non-Thrombogenic Low-Profile Percutaneous Atrioventricular Valve Prosthesis David Schwartzman; Vinay Badhwar; Antonio D’Amore; William Wagner; Young Jae Chun Janice Panza Licensed
 
11,773,391 A New Therapeutic and Diagnostic Target for SARS-COV-2 and Covid-19 Stephen Chan; Lloyd Harvey Katherine Gadacz Available for Licensing
 
11,773,075 Modulators of P97 AAA Atpase Activity Donna Huryn; Peter Wipf; Matthew LaPorte Maria Vanegas Available for Licensing
 
11,780,154 Extrusion Printing of Liquid Crystal Elastomers Ravi Meenakshisundaram; Taylor Ware; Cedric Ambulo; Jennifer Boothby; Julia Burroughs; Mohand Saed George Coulston Available for Licensing
 
11,779,647 Complex Coacervate for Controlled Release and Related Methods Yadong Wang; Eric Jeffries Janice Panza Available for Licensing
 
11,782,210 Sensing and/or Protective Layers for Optical Fiber-Based Sensors Using Atomic Layer Deposition Synthesis on Optical Fibers Paul Ohodnicki; Jung-Kun Lee; Yulin Liu George Coulston Available for Licensing
 
11,781,984 Fluorescent Method to Quantify Copper or Platinum Based on Catalysis Melissa Campbell; Dianne Pham; Kazunori Koide George Coulston Available for Licensing
 
11,786,569 Expression of Metabolic Modulators in Tumor Microenvironment to Improve Tumor Therapy Dayana Rivadeneira; Padmavathi Sampath; Stephen Thorne; Greg Delgoffe Maria Vanegas Licensed
 
11,787,846 EPHA2 T-Cell Epitopes and Uses Thereof Michael Kinch; Walter Storkus Alex Ducruet Licensed
 
11,793,961 Esophageal Temporary Occlusion Device and Method for Endotracheal Intubation and Orogastric Tube Insertion Philip Carullo; Young Jae Chun Janice Panza Available for Licensing
 
11,793,765 Vaginal Films Lisa Rohan Andrew Remes Optioned
 
11,793,983 Sonodynamic Therapy Using Microbubbles and Pulsed Wave Ultrasound Methods and Systems Xucai Chen; Flordeliza Villanueava; Bin Qin Katherine Gadacz Available for Licensing
 
11,793,863 Functionalized Microbubble Embodiments for Ultrasound-Mediated Treatment and Methods of Making and Using the Same Stephen D’Auria; Johyn Pacella; Xucai Chen; Francois Tchi Ho Yu; Thiruganesh Ramasamy Katherine Gadacz Available for Licensing
 
11,794,009 Devices, Systems and Methods for Treating Urological and Gastrointestinal Disorders by Electrical Stimulation of the Foot Changfeng Tai Maria Vanegas Available for Licensing