The University of Pittsburgh announced that Pitt innovators were issued 6 U.S. patents in September 2021.
Featured Patent: 11,129,846 “Method of Treating Severe Asthma”
Severe asthma accounts for 5-10 percent of asthma sufferers, but consumes up to 50 percent of asthma-related healthcare costs of $28 billion per year. Corticosteroids, a mainstay of asthma therapy, are ineffective at treating severe asthma, leading to more frequent emergency care and hospitalization. The innovators have shown that expression of IFN-y is significantly reduced in IRF5-deficient mice. An intervention to block IRF5 function in the lungs of severe asthmatics is therefore a promising new therapeutic modality by preventing airway hyperactivity.
For more information on this technology, contact Maria Vanegas at mvanegas@innovation.pitt.edu.
Below is a list of patents issued to Pitt innovators in Septembert 2021. You can also search the complete database of all Pitt innovations available for licensing.
Patent Number |
Title | Inventor(s) | Licensing Manager | Status | |||
11,111,253 | 6-ARYL-7 Substituted-3-(1H-PYRAZOL-5-YL)-7-H-[1,2,4] TRIAZOLO [3,4-B] [1,3,4] Thiadiazines as Inhibitors of the Stat3 Pathway with Anti-Proliferative Activity | Donna Huryn; Peter Wipf; Jennifer Grandis; Matthew LaPorte; Paul Johnston; Mark Schurdak; Raffaele Colombo | Maria Vanegas | Available for licensing | |||
11,117,936 | Affinity-Enhanced Monomeric Streptavidin Chimeric Antigen Receptor (CAR) | Jason Lohmueller | Andrew Remes | Available for licensing | |||
11,123,454 | Biodegradable, Thermally Responsive Injectable Hydrogel for Treatment of Ischemic Cardiomyopathy | Tomo Yoshizumi; William Wagner; Yang Zhu; Hongbin Jiang | Janice Panza | Available for licensing | |||
11,129,711 | Double Component Mandrel for Electrospun Stentless, Multi-Leaflet Valve Fabrication | Antonio D’Amore; William Wagner; Vinay Badhwar; Young Jae Chun | Janice Panza | Licensed | |||
11,129,875 | Osteoarthritis Treatment with Chemokine-Loaded Alginate Microparticles | Riccardo Gottardi; Steven Little; Daniel Desantis; Mintai Hwang | Janice Panza | Available for licensing | |||
11,129,846 | Method of Treating Severe Asthma | Anuradha Ray; Timothy Oriss; Prabir Ray; Sally Wenzel | Maria Vanegas | Available for licensing | |||