Pitt innovators were issued 12 U.S. patents in May 2025.
Featured patent: 12,307,657: System and Method for Quantifying the Extent of Disease from 2-D Images
University of Pittsburgh researchers have developed a machine learning method to quantify the extent of pneumonia and other thoracic diseases from two-dimensional (2D) x-ray images, improving the diagnostic ability of such images and reducing costs for patients, hospitals, and insurance companies. This software can be easily integrated into hospital cloud-based systems for point-of-care access and can even be used to trend disease progression between patient scans. A prototype is available and experimental data providing preliminary evidence for the feasibility of the proposed technology for analyzing the extent of emphysema from 2D chest x-ray images in a cohort of COPD patients and pneumonia in a cohort of COVID-19 patients. For more information on this technology, including licensing, contact us at partner@pitt.edu.
Below is a listing of all patents issued to Pitt innovators in April 2025. You can also search all Pitt technologies available for licensing.
| Patent Number |
Title | Inventor(s) | Licensing Manager | Status | |||
| 12,297,176 | Compounds and Methods for Inhibiting EMT Pathways to Treat Cancer, Organ Fibrosis, and Metabolic Disorders | Sebastien Comesse; Adam Daich; Martin Lawson; Catalin Pintiala; Abdelhadi Rebbaa | Kate Gadacz | Available for Licensing | |||
| 12,303,558 | Cancer Prevention and Therapy by Inhibiting Soluble Tumor Necrosis Factor | Nikola Vujanovic; Lazar Vujanonic | Maria Vanegas | Licensed | |||
| 12,294,124 | System and Method for Monitoring a Reactor System Using Optical Fiber-Based Sensors | Thomas Brown; Michael Buric; Peng Chen; Kirk Gerdes; Paul Ohodnicki; Jacob Poole | Connor Perryman | Available for Licensing | |||
| 12,290,500 | Anaplerotic Agents for Treatment of Disorders of Propionate and Long Chain Fat Metabolism | Al-Salid Mohsen; Gerard Vockley | Maria Vanegas | Available for Licensing | |||
| 12,303,533 | ECM Hydrogel for Treating Esophageal Inflammation | Stephen Badylak; Juan Diego Naranjo Gutierrez; Lindsey Saldin | Alex Ducruet | Licensed | |||
| 12,296,044 | Gel for Treating Periocular and/or Orbital Pathologies and Conditions | Morgan Dileo; Michael Washington; Jenny Yu | Janice Panza | Available for Licensing | |||
| 12,297,437 | Optogenetic Induction of Membraneless Organelles | Joseph Clarke; Christopher Donnelly | Andrew Remes | Available for Licensing | |||
| 12,291,504 | Small Molecule Inhibition of Sulfotransferase SULT1A3 | Mary Cacace; Ian Cook; Kristie Darrah; Alex Deiters; Thomas Leyh; Ting Wang | Andrew Remes | Available for Licensing | |||
| 11,292,327 | High Temperature Near-Field Probe for Sensing and Energy Harvesting Applications Based Upon Thermal Emission | Paul Ohodnicki; Sheng Shen | Connor Perryman | Available for Licensing | |||
| 12,297,725 | Control of Fracture Growth During Well Operations | Jose Adachi; Andrew Bunger; Amr Said El-Fayoumi; Qiao Lu; Karim Zaki | Tara Branstad | Available for Licensing | |||
| 12,307,657 | System and Method for Quantifying the Extent of Disease from 2-D Images | Jiantao Pu | Robert Racunas | Available for Licensing | |||
| 12,290,640 | Noninvasive, Regional Brain Thermal Stimulation | Eric Nofzinger; Jeffrey Schirm | Alex Ducruet | Available for Licensing |