Pitt innovators were issued11 patents in February 2023.
Featured Patent: 11,591,564: “Peptide Conjugated Hydrogel Substrate for the maintenance and Expansion of Human Pluripotent Stem Cells“
With ongoing clinical trials using human pluripotent stem cells (hPSCs), there is a need for rapid and controlled expansion of the cells to meet demand. Current approaches towards scalable hPSC culture use undefined animal products or expensive human-based proteins. Additionally, these products don’t support single-cell culture — which is necessary for large scale biomanufacturing — and result in only about 30 percent cell survival.
Pitt innovators from the lab of Ipsita Banerjee, associate professor in the Department of Chemical Engineering, have developed VitaCapsule, a low cost synthetic peptide-conjugated hydrogel system for hPSC manufacturing. This support system doubles hPSC survival rate compared to current culture methods and has applications in biomanufacturing and laboratory research.
For more information on this technology, including licensing, contact Janice Panza at jpanza@innovation.pitt.edu.
Below is a listing of all patents issued to Pitt innovators in January 2023. You can also search all available Pitt technologies.
Patent Number |
Title | Inventor(s) | Licensing Manager | Status | |||
11,575,127 | High Capacity, Air-Stable, Structurally Isomorphous Lithium Alloy Multilayer Porous Foams | Prashant Kumta; Prashanth Hanumantha; Pavithra Shanthi; Moni Datta; Oleg Velikikhatnyi | Janice Panza | Available for Licensing | |||
11,576,756 | Dental Abutment Screw Extractor | Ashley Smoots; Hannah Smith; Paul Kukunas; Fanying Sun; Tyler Hughes; Steve Kukunas | Janice Panza | Available for Licensing | |||
11,576,887 | Nitro-Oleic Acid Controlled Release Platform to Induce Regional Angiogenesis in Abdominal Wall Repair | Antonio D’Amore; Marco Fazzari; Bruce Freeman; William Wagner | Andrew Remes | Available for Licensing | |||
11,577,045 | Vibratory Devices for Phantom Limb Pain | Brianna Perry; Goeran Fiedler; Kevin Quinn | George Coulston | Available for Licensing | |||
11,583,613 | Hydrogel Systems for Skeletal Interfacial Tissue Regeneration Applied to Epiphyseal Growth Plate Repair | Juan Taboas; Jingming Chen | Janice Panza | Available for Licensing | |||
11,583,555 | Genetic Re-engineering of Immune Cells to Improve Metabolic Fitness for Immunotherapy | Greg Delgoffe | Maria Vanegas | Available for Licensing | |||
11,591,564 | Peptide Conjugated Hydrogel Substrate for the maintenance and Expansion of Human Pluripotent Stem Cells | Ipsita Banerjee; Prashant Kumta; Thomas Richardson | Janice Panza | Available for Licensing | |||
11,590,162 | Biodegradable, Antioxidant, Thermally Responsive Injectable Hydrogel for Treatment of Ischemic Cardiomyopathy | William Wagner; Yang Zhu; Yasumoto Matsumura; Munugesan Velayutham | Janice Panza | Available for Licensing | |||
11,590,266 | Biodegradable Iron-Containing Compositions, Methods of Preparing and Applications Thereof | Prashant Kumta; Oleg Velikokhatnyi; Moni Datta; Sung Jae Chung; Da-Tren Chou; Dae Ho Hong; Partha Sasha | Janice Panza | Available for Licensing | |||
11,589,906 | Biodegradable, Magnesium-Containing Bone Screws, Methods for Their Preparation and Medical Applications Thereof | John Holmes; Alehandro Almarza; William Chung; Sarah Henderson | Janice Panza | Available for Licensing | |||
11,594,753 | Cathodes and Electrolytes for Rechargeable Magnesium Batteries and Methods of Manufacture | Prashant Kumta; Partha Saha; Moni Datta; Ayyakkannu Manivannan | Janice Panza | Available for Licensing | |||