The University of Pittsburgh announced that Pitt innovators were issued nine U.S. patents in February 2021.
Featured Patent: 10,913,776 “Zika Virus Vaccines”
Zika flavivirus has been declared a global emergency by the World Health Organization due to the number of babies born with microencephaly and neurological disorders as a result of maternal zika infections. Andrea Gambotto, associate professor of surgery, and colleagues, have developed a recombinant adenoviral vector vaccine combined with skin-targeting vaccine delivery technology to create advantages in immunogenicity and safety.
The vaccine delivery strategy utilizes an intracutaneous microneedle array (MNA)-based delivery system, found to be superior to intramuscular administration in both the potency and duration of the induced immune response. The MNA vaccine delivery system also affords unique advantages in reproducibility, safety, manufacturing, and distribution, by relieving pressure on the cost-intensive “cold chain” required
For more information on this innovation, including licensing, contact Maria Vanegas at mvanegas@innovation.pitt.edu
Below is a list of patents issued to Pitt innovators in February 2021. To search the database of all Pitt innovations available for licensing, click here.
Patent Number |
Title | Inventor(s) | Licensing Manager | Status | |||
10,906,203 | Apparatus and Method for Joining of Carbide Ceramics | Jung-Kun Lee; Ian Nettleship; Ryan Read | George Coulston | Available for Licensing | |||
10,906,876 | Tetrahydroisoquinol II as Selective NADPH Oxidase 2 Inhibitors | Patrick Pagano; Peter Wipf; Maria Cifuentes; Pagano; Erin Skoda | Abhishek Sangal | Available for Licensing | |||
10,912,688 | Mobility Enhancement Wheelchair | Hongwu Wang; Rory Cooper; Chengshiu Chung; Jorge Candiotti; Garrett Grindle; Jonathan Pearlman; Brandon Daveler | George Coulston | Available for Licensing | |||
10,913,776 | Zika Virus Vaccines | Andrea Gambotto; Eun Kim; Louis Falo; Geza Erdos | Maria Vanegas | Available for Licensing | |||
10,913,951 | Silencing of HNF4A-P2 Isoforms With SIRNA to Improve Hepatocyte Function in Liver Failure | Ramon Alberola; Jose Maria Ballbe | Abhishek Sangal | Not Available for Licensing | |||
10,920,264 | ACYL-COA Dehydrogenases Micro/Nano Enzyme Assay | Gerald Vockley; Al-Walid Mohsen | Maria Vanegas | Available for Licensing | |||
10,928,384 | Antigen Presenting Cell Assay | Rakesh Sindhi; Chethan Kumar | Maria Vanegas | Licensed | |||
10,925,869 | Compositions and Methods for Treating Pulmonary Vascular Disease | Stephen Chan; Thomas Bertero | Maria Vanegas | Available for Licensing | |||
3,332,037 | Methods for Predicting Prostate Cancer | Jianhua Luo; Yanping Yu; Chien-Cheng Tseng; Shuchang Liu; George Michalopoulos; Joel Nelson | Andrew Remes | Available for Licensing |