December 7, 2018

The University of Pittsburgh announced that Pitt innovators were issued seven patents in November 2018.

Featured Patent: U.S. 10,137,236 “Self-Regulating Device for Modulating Inflammation”

The innovators, led by Yoram Vodovotz, Professor of Surgery, Immunology, Computational and Systems Biology and Bioengineering, have conceived a medical device that employs mathematical models of inflammation to create negative feedback proportional to the degree of inflammatory stimulus that has potential applications for acute inflammatory diseases such as sepsis or trauma, chronic conditions such as rheumatoid arthritis, and cancer. For more information on this technology, including licensing, contact Maria Vanegas at

Below is a list of all patents issued to Pitt innovators in November 2018. To search the database of all Pitt innovations available for licensing, click here.


Title   Inventor(s)   Licensing Manager      Status
10,119,119 Polysiloxane Substrates with Highly-Tunable Elastic Modulus Adam Feinberg; James Funderburgh; Rachelle Simko Maria Vanegas Available for Licensing
10,125,184 Apolipoprotein E Polypeptides and Their Use Tianyi Wang; Shufeng Liu; Fan Daping Abhishek Sangal Available for Licensing
10,126,305 Proteomic Biomarkers of Sepsis in Elderly Patients Zhiyun Cao; John Kellum Jr.; Derek Angus; Rena Sowell Robinson; Sachin Purushottam Yende Alex Ducruet Available for Licensing
10,131,699 EPHA2 T-Cell Epitopes and Uses Thereof Walter Storkus; Michael Kinch Alex Ducruet Licensed
10,137,236 Self-Regulating Device for Modulating Inflammation Yoram Vodovotz; Gregory Constantine; Jorg Gerlach; Qi Mi; Maxim Mikheev; David Okonkwo; Alexey Solovyev Maria Vanegas Available for Licensing
10,136,808 Optical Coherence Tomography as a Rapid, Accurate, Non-Contact Method of Visualizing the Palisades of Vogt Kira Lathrop; Lawrence Kagemann; Joel Schuman Janice Panza Available for Licensing
10,137,210 Thioflavin Derivatives for Use in Antemortem Diagnosis of Alzheimer’s Disease and In Vivo Imaging and Prevention of Amyloid Deposition William Klunk; Chester Mathis; Yanming Wang Alex Ducruet Licensed