Hunter Family Foundation Traumatic Brain Injury Translational Research Program

 

The University of Pittsburgh Hunter Family Foundation Traumatic Brain Injury Translational Research Program (the Hunter Program) was established to drive discoveries and technologies in the areas of nervous system injury, inflammation, and disease identified in the lab closer to products and treatments for patients. Made possible through the generosity of the Hunter Family, the program is designed to bridge the gap between academic bench science and commercial development by corporate partners or through the creation of new companies.

A single $100,000 award is granted each year to further develop Pitt technologies addressing unmet needs in the field of neuroscience with compelling proof-of-principle or proof-of-concept data.

The Hunter Program, administered by the Office of Innovation and Entrepreneurship (OIE), provides:

  • Funding for key proof-of-concept or validation studies for technologies in the field of neuroscience and  
  • Innovation and commercialization education and training.  

Funding is granted in the form of either: 

  • Proof-of-Concept and Prototype Funds to support key proof-of-concept studies, including in vivo experiments, hit-to-lead studies, prototype development, or benchtop testing or   
  • Precommercialization Project Funds to support key validation studies, including IND/IDE-enabling studies, pharm/tox studies, or developability assays. 

Projects must be focused on advancing technologies towards commercialization and the use of innovations outside of the academic environment. Funding cannot be used for proof-of-principle or hypothesis-based research.

About The Hunter Program

  • The Hunter Family Foundation Traumatic Brain Injury Translational Research Program is a competitive innovation funding program for technologies addressing unmet needs in the field of neuroscience.  
  • A single $100,000 award is granted each year in the form of either: 
    • Proof-of-Concept and Prototype Funds to support key proof-of-concept studies, including in vivo experiments, hit-to-lead studies, prototype development, or benchtop testing or  
    • Precommercialization Project Funds to support key validation studies, including IND/IDE-enabling studies, pharm/tox studies, or developability assays. 
  • Awardees are required to communicate and engage with OIE regularly to track project progress and to participate in innovation and commercialization education and events. Communications include a project kickoff meeting, progress reports, and update meetings. 
  • Funding is released according to a milestone-based project plan developed in collaboration with OIE. Each project will have 1-3 quantifiable technical/scientific milestones and 1-2 business development milestones. Examples of business development milestones include customer discovery training, curated education, market assessments, or outreach to potential industry partners.  
  • Projects are expected to start within one month of the award date (pending any necessary regulatory approvals or purchasing contracts) and should be completed within 12 months of the project start date. Applicants should ensure that timelines are appropriate for the proposed milestones and that the resources are available to meet the Hunter Program requirements and timeline. 
  • Desired outcomes of funded projects included: 
    • Development and de-risking of Pitt intellectual property, 
    • Followon federal, foundation, or industry funding, 
    • Creation of commercialization opportunities through industry partnerships or new venture creation, and/or 
    • Impactful use of Pitt technology outside of the lab. 

  • The Hunter Program is open to Pitt faculty, postdocs, students, and staff. Postdocs, students, and staff must identify a Pitt faculty member to serve as the PI. 
  • Projects must support the further development or validation of intellectual property assigned to Pitt.  
  • An invention disclosure is not required to apply to the Hunter Program. However, applicants selected for funding will be required to submit an invention disclosure to OIE before an award can be issued 
  • Under certain circumstances, funding from the Hunter Program may be used to support IP co-owned by Pitt and another academic institution. Investigators are encouraged to connect with their licensing manager regarding the ownership of their IP prior to submitting an application. 
  • The technology must be unencumbered from obligations that would prevent the University from moving forward with commercialization. The technology should be available for licensing to a Pitt licensed startup company or external third party and not subject to any pre-existing options, licenses, or corporate sponsored research agreements. 
  • Projects with funding from another source to complete the same work are not eligible. Applicants should not propose projects that have already been funded through a grant, contract, or other funding source, including Pitt internal funding mechanisms. 

  • The Hunter Program grants a single award each year selected through a competitive request for proposals.  
  • Applications are submitted on Pitt InfoReady and are reviewed by OIE and an advisory board with domain expertise 
  • Final technical/scientific and business development milestones are developed in collaboration with OIE. 

The goal of the Hunter Program is to accelerate the development of novel technologies discovered in the lab into services and products addressing unmet health needs in the field of neuroscience. Projects are selected for commercialization potential and societal impact using the following criteria 

  • Eligibility and fit for the Hunter Program
  • Scientific merit and novelty 
  • Status and strength of the intellectual property 
  • Market opportunity 
  • Customer and/or industry feedback 
  • Feasibility of the proposed project 
  • Team qualifications 

Funds from the Hunter Program may only be used for the direct costs of the activities detailed in the approved project plan and budget. Non-faculty personnel costs will be considered, but it is preferred that personnel costs are limited. 

Eligible expenses include:

  • Lab supplies, research animals, prototyping supplies, fabrication or manufacturing expenses, and trial costs 
  • Postdoc, student, and technician salaries
  • Consultants, contract research organizations (CRO), and service providers. All providers are required to assign IP rights to the University prior to beginning work
  • With prior approval from OIE, travel costs related directly to meeting an approved milestone

Ineligible expenses include:

  • Overhead/indirect costs
  • Faculty salaries
  • Tuition
  • Travel
  • Capital equipment
  • Computer equipment
  • Publication costs

  • Applications Open: February 1, 2025 
  • Applications Close: February 28, 2025 
  • Anticipated Award Date: early April 2025 
  • Anticipated Project Start Date: May or June 2025 

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