April 2, 2020
The University of Pittsburgh announced that Pitt innovators were issued 14 U.S. patents in March 2020.
Featured Patent: U.S. 10,547,376: “Layer by Layer Coated Mesh for Local Release of Bioactive Proteins”
The host immune response to therapeutic implants can cause severe complications. By applying a new active agent-eluting coating to implantable biomaterials, researchers are able to modulate the local immune reaction and reduce implant-related complications and /or improved integration of the biomaterial into the host tissue. The active agent-eluting coating can be applied to impolanted materials such as mesh, sutures, wound dressings, intraocular lenses, decellularized matrices, bone plates, joint replacements, biosensors, catheters, pacemakers, artificial organs, stents, ventricular assist devices, and neural electrodes, among others, to mitigate the inflammatory reaction to the implant and promote better implant integration into the host tissue.
For more information on this technology, including licensing, contact Janice Panza at email@example.com.
Below is a list of all patents issued to Pitt innovators in March 2020. To search the database of all Pitt innovations available for licensing, click here.
|10,547,376||Layer by Layer Coated Mesh for Local Release of Bio-Active Proteins||Daniel Hachim; Bryan Brown||Janice Panza||Available for Licensing|
|10,575,723||Mapping of Internal Features on En Face Imagery||Lawrence Kagemann Jr.; Joel Schuman; Sayoko Moroi||Janice Panza||Available for Licensing|
|10,576,115||Oncolytic HSV Vectors||Joseph Glorioso; Hioaki Uchida; Justus Cohen; Paola Grandi||Maria Vanegas||Licensed|
|10,576,051||Nitrated-Fatty Acids Modulation of Type II Diabetes||Bruce Freeman; Francisco Schopfer||Andrew Remes||Licensed|
|10,582,996||Biodegradable Vascular Grafts||Yadong Wang||Janice Panza||Available for Licensing|
|10,582,995||Intra-Oral Prostheses and Other Anatomical Prostheses||Neil Gildener-Leapman; Youngjae Chun||Janice Panza||Available for Licensing|
|10,583,004||Retrievable Self-Expanding Non-Thrombogenic Low-Profile Percutaneous Atrioventricular Valve Prosthesis||Youngjae Chun; Vinay Badhwar; William Wagner; Antonio D’Amore; David Schwartzman||Janice Panza||Available for Licensing|
|10,589,002||Biodegradable, Thermally Responsive Injectable Hydrogel for Treatment of Ischemic Cardiomyopathy||Tomo Yoshizumi; William Wagner; Yang Zhu; Hongbin Jiang||Janice Panza||Available for Licensing|
|10,588,853||Custom Designed Microbubble Contrast Agents and Techniques of Ultrasound||Andy Carson; Flordeliza Villanueva; Charles McTiernan; Jianjun Wang||Abhishek Sangal||Available for Licensing|
|10,596,237||Identification of Pneumocystis Antigens and Uses Thereof||Jay Kolls; Michael Zheng; Yang Cai; David Ricks; Taylor Eddens||Maria Vanegas||Available for Licensing|
|10,596,197||Red Blood Cell Membrane-Derived Microparticles and Their Use for the Treatment of Lung Disesase||Janet Lee||Maria Vanegas||Available for Licensing|
|10,603,156||Biodegradable Vascular Grafts||Robert Allen; Chelsea Stowell; Yadong Wang||Janice Panza||Available for Licensing|
|10,604,827||Biodegradable Metal Alloys||Da-Tren Chou; Partha Saha; Dae Ho Hong; Prashant Kumta||Janice Panza||Available for Licensing|
|10,603,321||Small Molecules Targeting HIV-1 NEF||Thomas Smithgall||Andrew Remes||Available for Licensing|