February 11, 2019

The University of Pittsburgh announced that Pitt innovators were issued 17 U.S. patents in January 2019.

Featured Patent: U.S. 10,167,519 “Fusion Gene Associated with Progressive Prostate Cancer”

Jianhua Luo, professor in the Department of Pathology, and colleagues have developed methods and compositions for determining whether a person having prostate cancer is at greater risk of developing progressive disease, and methods of treating the subjects. It is based in part on the discovery that approximately 90% of men carrying specific fusion genes experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy, while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based in part on the discovery that no patient studied survived five years without recurrence if their primary prostate cancer contained a TRMT11-GRIK2 or MTOR-TP53BP1 fusion gene.

For more information on this innovation, contact Andrew Remes at aremes@innovation.pitt.edu.


Below is a list of all patents issued to Pitt innovators in January 2019. To search the database of all Pitt innovations available for licensing, click here.

Title   Inventor(s)   Licensing Manager      Status
10,167,265 Treatment of Pulmonary and Other Conditions Raju Reddy Maria Vanegas Optioned
10,167,519 Fusion Gene Associated with Progressive Prostate Cancer Jianhua Luo; Yanping Yu; Joel Nelson; George Michalopoulos; Chien-Cheng Tseng; Ying Ding Andrew Remes Available for Licensing
10,172,848 Gap Junction Enhancing Agents for Treatment of Necrotizing Enterocolitis and Inflammatory Bowel Disease David Hackman Maria Vanegas Available for Licensing
10,174,377 Method for Diagnosing and Assessing Risk of Pancreatitis Using Genetic Variants David Whitcomb Abhishek Sangal Available for Licensing
10,172,795 Formulations and Carrier Systems Including Compound Interactive Domains Xiang Gao; Song Li; Peter Wipf; Michael Epperly; Joel Greenberger Andrew Remes Available for Licensing
10,173,265 Method for Producing Small Metal Alloy Nanoparticles Andrew Dewar; Christopher Andolina; Jill Millstone Janice Panza Available for Licensing
10,174,341 Non-Toxic HSV Vectors for Efficient Gene Delivery Applications and Complementing Cells for Their Production Justus Cohen; Joseph Glorioso; Yoshitaka Miyagawa; Darren Wolfe; James Wechuck; David Krisky Maria Vanegas Licensed
10,172,923 Use of Endostatin Peptides for the Treatment of Fibrosis Carol Feghali-Bostwick; Yukie Yamaguchi Maria Vanegas Licensed
10,172, 893 Oncolytic HSV Vector Justus Cohen; Hiroaki Uchida; Joseph Glorioso; Paola Grandi Maria Vanegas Licensed
10,174,031 Calcium Channel Agonists Peter Wipf; Stephen Meriney; Mary Liang Andrew Remes Optioned
10,179,111 Treating Soft Tissue Via Controlled Drug Release Peter Alexander; Riccardo Gottardi; Patrick Bianconi; Steven Little Alex Ducruet Available for Licensing
10,179,805 Computationally Optimized Broadly Reactive Antigens for Human and Avian H5N1 Influenza Ted Ross; Corey Crevar; Brendan Giles Andrew Remes Licensed
10,179,192 Injectable Peripheral Nerve Specific Hydrogel Bryan Brown; Jonathan Cheetham Janice Panza Licensed
10,184,152 Transcriptional Signature for Chlamydial Pelvic Inflammatory Disease Catehrine O’Connell; Toni Darville; Xiaojing Zheng Abhishek Sangal Available for Licensing
10,182,711 Method and Apparatus for Aiding in the Diagnosis of Otitis Media by Classifying Tympanic Membrane Images Nader Shaikh; Alejandro Hoberman; Jelena Kovacevic; Anupama Kuruvilla Carolyn Weber Available for Licensing
10,183,977 Stabilized Stat3 Decoy Oligonucleotides and Uses Thereof Jennifer Grandis; Daniel Johnson; Danith Ly Maria Vanegas Optioned
10,188,686 Oncolytic HSV Vector Paola Grandi; Justus Cohen; Hiroaki Uchida; Joseph Glorioso Maria Vanegas Licensed