February 11, 2019
The University of Pittsburgh announced that Pitt innovators were issued 17 U.S. patents in January 2019.
Featured Patent: U.S. 10,167,519 “Fusion Gene Associated with Progressive Prostate Cancer”
Jianhua Luo, professor in the Department of Pathology, and colleagues have developed methods and compositions for determining whether a person having prostate cancer is at greater risk of developing progressive disease, and methods of treating the subjects. It is based in part on the discovery that approximately 90% of men carrying specific fusion genes experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy, while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based in part on the discovery that no patient studied survived five years without recurrence if their primary prostate cancer contained a TRMT11-GRIK2 or MTOR-TP53BP1 fusion gene.
For more information on this innovation, contact Andrew Remes at firstname.lastname@example.org.
Below is a list of all patents issued to Pitt innovators in January 2019. To search the database of all Pitt innovations available for licensing, click here.
|10,167,265||Treatment of Pulmonary and Other Conditions||Raju Reddy||Maria Vanegas||Optioned|
|10,167,519||Fusion Gene Associated with Progressive Prostate Cancer||Jianhua Luo; Yanping Yu; Joel Nelson; George Michalopoulos; Chien-Cheng Tseng; Ying Ding||Andrew Remes||Available for Licensing|
|10,172,848||Gap Junction Enhancing Agents for Treatment of Necrotizing Enterocolitis and Inflammatory Bowel Disease||David Hackman||Maria Vanegas||Available for Licensing|
|10,174,377||Method for Diagnosing and Assessing Risk of Pancreatitis Using Genetic Variants||David Whitcomb||Abhishek Sangal||Available for Licensing|
|10,172,795||Formulations and Carrier Systems Including Compound Interactive Domains||Xiang Gao; Song Li; Peter Wipf; Michael Epperly; Joel Greenberger||Andrew Remes||Available for Licensing|
|10,173,265||Method for Producing Small Metal Alloy Nanoparticles||Andrew Dewar; Christopher Andolina; Jill Millstone||Janice Panza||Available for Licensing|
|10,174,341||Non-Toxic HSV Vectors for Efficient Gene Delivery Applications and Complementing Cells for Their Production||Justus Cohen; Joseph Glorioso; Yoshitaka Miyagawa; Darren Wolfe; James Wechuck; David Krisky||Maria Vanegas||Licensed|
|10,172,923||Use of Endostatin Peptides for the Treatment of Fibrosis||Carol Feghali-Bostwick; Yukie Yamaguchi||Maria Vanegas||Licensed|
|10,172, 893||Oncolytic HSV Vector||Justus Cohen; Hiroaki Uchida; Joseph Glorioso; Paola Grandi||Maria Vanegas||Licensed|
|10,174,031||Calcium Channel Agonists||Peter Wipf; Stephen Meriney; Mary Liang||Andrew Remes||Optioned|
|10,179,111||Treating Soft Tissue Via Controlled Drug Release||Peter Alexander; Riccardo Gottardi; Patrick Bianconi; Steven Little||Alex Ducruet||Available for Licensing|
|10,179,805||Computationally Optimized Broadly Reactive Antigens for Human and Avian H5N1 Influenza||Ted Ross; Corey Crevar; Brendan Giles||Andrew Remes||Licensed|
|10,179,192||Injectable Peripheral Nerve Specific Hydrogel||Bryan Brown; Jonathan Cheetham||Janice Panza||Licensed|
|10,184,152||Transcriptional Signature for Chlamydial Pelvic Inflammatory Disease||Catehrine O’Connell; Toni Darville; Xiaojing Zheng||Abhishek Sangal||Available for Licensing|
|10,182,711||Method and Apparatus for Aiding in the Diagnosis of Otitis Media by Classifying Tympanic Membrane Images||Nader Shaikh; Alejandro Hoberman; Jelena Kovacevic; Anupama Kuruvilla||Carolyn Weber||Available for Licensing|
|10,183,977||Stabilized Stat3 Decoy Oligonucleotides and Uses Thereof||Jennifer Grandis; Daniel Johnson; Danith Ly||Maria Vanegas||Optioned|
|10,188,686||Oncolytic HSV Vector||Paola Grandi; Justus Cohen; Hiroaki Uchida; Joseph Glorioso||Maria Vanegas||Licensed|