September 10, 2020

The University of Pittsburgh announced that Pitt innovators were issued 15 U.S. patents in August 2020.

Featured Patent: 10,10,744,308Novel Low-Profile Ventriculoamniotic Shunt for Fetal Acqueductal Stenosis

Fetal obstructive hydrocephalus is a condition that causes permanent brain damage resulting from intracerebral pressure from the obstruction of the flow of cerebrospinal fluid. A University of Pittsburgh innovation team led by YoungJae Chun, associate professor of engineering, is developing a shunt for in-utero drainage of cerebrospinal fluid. The device features percutaneous ultrasound-guided insertion to minimize risk to the mother; is constructed of FDA-approved materials; includes anchoring system to prevent dislodgement or migration and a one-way valve to prevent inflow of amniotic fluid into the cerebral ventricles. Additional intellectual property related to this device has been developed and is in prosecution.

For more information on these innovations, including licensing, contact Janice Panza at

Below is a list of patents issued to Pitt innovators in August 2020. To search the database of all Pitt innovations available for licensing, click here.


Title   Inventor(s)   Licensing Manager        Status
10,732,214 Communication-Less Fault Section Identification for Hybrid HVDC Transmission Systems Patrick Lewis; Brandon Grainger; Hashim Al Hassan; Gregory Reed Janice Panza Available for licensing
10,729,711 Methods for Treatment Using Small Molecule Potassium-Sparing Diuretics and Natriuretics Edwin Jackson; Stevan Tofovic Andrew Remes Optioned
10,729,813 Extracellular Matrix-Derived Gels and Related Methods Stephen Badylak; Donald Freytes Alex Ducruet Licensed
10,736,991 Non-Gelling Soluble Extracellular Matrix with Biological Activity Timothy Keane Jr.; Lisa White; Stephen Badylak Alex Ducruet Licensed
10,738,152 Methods of Electrospinning and Compositions Made Therefrom Eric Jeffries; Yadong Wang; Robert Allen Janice Panza Available for licensing
10,736,988 Bone Substitute Nanocomposites and Methods of Synthesis Using Multiphosphorylated Peptides Elia Beniash; Charles Sfeir Janice Panza Available for licensing
10,737,083 Bioactive Components Conjugated to Substrates of Microneedle Arrays Louis Falo Jr.; Geza Erdos Alex Ducruet Available for licensing
10,748,453 Myringotomy Surgical Training Device with Real-Time and Stored Feedback on Performance Molly Knewtson; Noel Jabbour; Jonathan Kenneson; Joseph Samosky Carolyn Weber Available for licensing
10,744,308 Novel Low-Profile Ventriculoamniotic Shunt for Fetal Acqueductal Stenosis Stephen Emery; Yanfei Chen; Young Jae Chun; Stephanie Green; William Wagner; Xinahu Gu Janice Panza Available for licensing
10,744,106 Reversibly Protected Thiolated Electrophilic Fatty Acids as Prodrugs Bruce Freeman; Francisco Schopfer; Nicholas Kah Hock Khoo; Steven Woodcock Andrew Remes Licensed
10,751,273 Compounds for the Treatment of Pathologies Associated with Aging and Degenerative Disorders Laura Niedernhofer; Paul Robbins; Peter Wipf Andrew Remes Optioned
10,751,248 Automatic Chest Compression Systems That Incorporate Biological Feedback David Salcido; James Menegazzi; Robert Tisherman; Matthew Sundermann Janice Panza Available for licensing
10,755,138 Systems and Methods for Finding Regions of Interest in Hematoxylin and Eosin (H&E) Stained Tissue Images and Quantifying Intratumor Cellular Spatial Heterogeneity in Multiplexed/Hyperplexed fluorescent Tissue Images Srinivas Chennubholtla; Douglass Taylor Robert Racunas Licensed
10,751,310 Prevention, Treatment and Reversal of Disease Using Therapeutically Effective Amounts of Dicarboxylic Acid Compounds Bruce Freeman; Francisco Schopfer Andrew Remes Licensed
10,752,629 Calcium Channel Agonists Peter Wipf; Stephen Meriney; Mary Liang Andrew Remes Optioned