University of Pittsburgh Announces Patents Issued in December 2020

Posted on by Mike Yeomans

January 20, 2020

The University of Pittsburgh announced that Pitt innovators were issued 16 U.S. patents in December 2020.

Featured Patent: 10,851,354 “TRPV1Modulatory Gene Product That Affects TRPV1-Specific Pain Behavioral Responses Identified in a Functional Screen of an HSV-Based cDNA Library”

Using herpes simplex virus (HSV) gene vectors, Pitt researchers from the lab of Joseph Glorioso, professor of microbiology and molecular genetics, were able to screen for and isolate a specific gene that can target pain-related behaviors associated with TRPV1, a gene implicated in the chronic pain state of patients with arthritis, cancer, cystitis, diabetic neuropathy, and post-herpetic neuralgia. Excitingly, the gene product is highly specific for TRPV1 and does not affect genes TRPM8 or TRPA1, which are involved in a variety of important responses including touch, cold, and other sensations that are undesirable to alter. This technology has broad and flexible applicability for the treatment of disease and associated chronic pain.

For more information on this innovation, including licensing, contact Maria Vanegas at mvanegas@innovation.pitt.edu.

Below is a list of patents issued to Pitt innovators in December 2020. To search the database of all Pitt innovations available for licensing, click here.

 

Patent
Number		 Title   Inventor(s)   Licensing Manager        Status
 
10,849,667 Biodegradable, Magnesium-Containing Bone Screws, Methods for Their Preparation and Medical Applications Thereof John Holmes; Alejandro Almarza; William Chung; Sarah Henderson Janice Panza Available for licensing
 
10,849,519 Wearable Cardiac Electrophysiology Measurement Devices, Software, Systems and Methods Matthew Jones; George Mendenhall Janice Panza Licensed
   
10,851,354 TRPV1Modulatory Gene Product That Affects TRPV1-Specific Pain Behavioral Responses Identified in a Functional Screen of an HSV-Based cDNA Library William Goins; Joseph Glorioso; Justus Cohen; Bonnie Reinhart Maria Vanegas Available for Licensing
 
10,851,153 Compositions and Methods for the Treatment of Carboxyhemoglobinem Jesus Bravo; Mark Gladwin Maria Vanegas Licensed
 
10,857,112 Small Molecule Inhibitors of RNA Binding Motif (RBM) Proteins for the Treatment of Acute Cellular Injury Travis Jackson; Jonathan Verrier; Patrick Kochanek Maria Vanegas Available for licensing
 
10,858,381 Antioxidant Compounds and Their Use Noah Snyder; Xinyan Cui; Kasey Catt; James Eles Janice Panza Licensed
 
10,876,041 Carbon Dioxide and Polymer Compositions for Permeability Control and Sealing Robert Enick Janice Panza Available for licensing
 
10,864,234 Stem Cell-Based Technologies for Avian Skeletal Tissue Engineering and Regeneration Rocky Tuan Janice Panza Available for Licensing
 
10,865,228 Computationally Optimized Broadly Reactive Antigens Ted Ross; Corey Crevar; Brendan Giles Andrew Remes Licensed
 
10,869,629 Deep Learning for Classification of Swallows Ervin Sejdic; James Coyle; Amro El-Jaroudi; Zhi-Hong Mao; Mingui Sun Janice Panza Available for Licensing
 
10,869,866 Benzathine Analogs Beibei Chen; Rama Mallampalli Maria Vanegas Licensed
 
10,870,918 Synthesis of Structured Carbon Material From Organic Materials Feng Zhou; Haitao Liu George Coulston Available for Licensing
 
10,869,850 Nitrated-Fatty Acids Modulation of Type II Diabetes Bruce Freeman; Francisco Schopfer Andrew Remes Licensed
 
10,874,730 Interleukin-13 Receptor Alpha2 Peptide-Based Cancer Vaccines Hideho Okada Alex Ducruet Licensed
 
10,876,111 Methods and Materials for Cloning Functional T Cell Receptors From Single T Cells Adriana Neves; Mark Shlomchik; Eduardo Neves; Constantinos Panousis; Alexander Rowe Jeffrey Depp Licensed
 
10,878,977 Compositions Including Nano-Particles and a Nano-Structured Support Matrix and Methods of Preparation as Reversible High Capacity Anodes in Energy Storage Systems Prashanth Hanumantha; Prashant Kumta; Bharat Gattu; Wei Wang Janice Panza Available for Licensing